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Pregnant people who are vaccinated are less likely to contract COVID-19 than unvaccinated pregnant people, and those vaccinated and boosted are less likely to get COVID than those who are vaccinated only, according to the first-ever large study of boosters and pregnancy.

Scientists from the Hadlock and Hood-Price Lab at ISB have published new research in the JMIR Public Health and Surveillance journal. The work explores the National Institute of Health (NIH) recommendation for prophylactic anticoagulant use for pregnant patients hospitalized for the manifestation of COVID-19.

Dr. Jennifer Hadlock – an expert in machine learning, immune-mediated inflammatory disease, and maternal/fetal health – has been promoted to associate professor. The Hadlock Lab is an interdisciplinary team that aims to accelerate translational research by integrating clinical data into systems biology at scale.

ISB researchers have constructed biological body mass index (BMI) measures that offer a more accurate representation of metabolic health and are more varied, informative and actionable than the traditional, long-used BMI equation. The work was published in the journal Nature Medicine. 

A just-published study provides new information about which hospitalized COVID-19 patients are most likely to need mechanical ventilation or to die. The ISB-led work shows that vital signs and lab results at the time of hospital admission are the most accurate predictors of disease severity, more so than comorbidities and demographics.

Researchers have identified several factors that can be measured at the initial point of COVID-19 diagnosis that anticipate if a patient is likely to develop long COVID. They also found that mild cases of COVID-19, not just severe cases, are associated with long COVID. Their findings were published by the journal Cell.