Publications

Hwang, Y. M., Roper, R. T., Piekos, S. N., Enquobahrie, D. A., Hebert, M. F., Paquette, A. G., Baloni, P., Price, N. D., Hood, L., & Hadlock, J. J. (2024). Timing of selective serotonin reuptake inhibitor use and risk for preterm birth and related adverse events: with a consideration of the COVID-19 pandemic period. The Journal of Maternal-Fetal & Neonatal Medicine, 37(1), 2313364. https://doi.org/10.1080/14767058.2024.2313364 Cite Download
Hwang, Y. M., Wei, Q., Piekos, S. N., Vemuri, B., Sevda Molani, Mease, P., Hood, L., & Hadlock, J. (2024). Maternal-fetal outcomes in patients with immune-mediated inflammatory diseases, with consideration of comorbidities: a retrospective cohort study in a large U.S. healthcare system. EClinicalMedicine, 0(0). https://doi.org/10.1016/j.eclinm.2024.102435 Cite Download
Baumgartner, A., Robinson, M., Huang, S., Hadlock, J., & Funk, C. (2023). Integration of multiple single cell microglial datasets reveals radial differentiation into long‐lived substates associated with Alzheimer’s pathology. Alzheimer’s & Dementia, 19. https://doi.org/10.1002/alz.080693 Cite
Hwang, Y. M., Wei, Q., Piekos, S. N., Vemuri, B., Molani, S., Mease, P., Hood, L., & Hadlock, J. J. (2023). Maternal-fetal outcomes in patients with immune mediated inflammatory diseases, with consideration of comorbidities: a retrospective cohort study in a large U.S. healthcare system. MedRxiv: The Preprint Server for Health Sciences, 2023.08.07.23293726. https://doi.org/10.1101/2023.08.07.23293726 Cite Download
Piekos, S. N., Hwang, Y. M., Roper, R. T., Sorensen, T., Price, N. D., Hood, L., & Hadlock, J. J. (2023). Effect of COVID-19 vaccination and booster on maternal-fetal outcomes: a retrospective cohort study. The Lancet. Digital Health, 5(9), e594–e606. https://doi.org/10.1016/S2589-7500(23)00093-6 Cite Download
Wei, Q., Mease, P. J., Chiorean, M., Iles-Shih, L., Matos, W. F., Baumgartner, A., Molani, S., Hwang, Y. M., Belhu, B., Ralevski, A., & Hadlock, J. (2023). Risk factors for severe COVID-19 outcomes: a study of immune-mediated inflammatory diseases, immunomodulatory medications, and comorbidities in a large US healthcare system. MedRxiv: The Preprint Server for Health Sciences, 2023.06.26.23291904. https://doi.org/10.1101/2023.06.26.23291904 Cite Download
Fecho, K., Bizon, C., Issabekova, T., Moxon, S., Thessen, A. E., Abdollahi, S., Baranzini, S. E., Belhu, B., Byrd, W. E., Chung, L., Crouse, A., Duby, M. P., Ferguson, S., Foksinska, A., Forero, L., Friedman, J., Gardner, V., Glusman, G., Hadlock, J., … Consortium, T. B. D. T. (2023). An approach for collaborative development of a federated biomedical knowledge graph-based question-answering system: Question-of-the-Month challenges. Journal of Clinical and Translational Science, 7(1), e214. https://doi.org/10.1017/cts.2023.619 Cite Download
Hwang, Y.-M., Piekos, S., Sorensen, T., Hood, L., & Hadlock, J. (2023). Adoption of a National Prophylactic Anticoagulation Guideline for Hospitalized Pregnant Women with COVID-19: Retrospective Cohort Study. JMIR Public Health and Surveillance. https://doi.org/10.2196/45586 Cite
Watanabe, K., Wilmanski, T., Diener, C., Earls, J. C., Zimmer, A., Lincoln, B., Hadlock, J. J., Lovejoy, J. C., Gibbons, S. M., Magis, A. T., Hood, L., Price, N. D., & Rappaport, N. (2023). Multiomic signatures of body mass index identify heterogeneous health phenotypes and responses to a lifestyle intervention. Nature Medicine, 29(4), 996–1008. https://doi.org/10.1038/s41591-023-02248-0 Cite Download
Hwang, Y. M., Roper, R. T., Piekos, S. N., Enquobahrie, D. A., Hebert, M. F., Paquette, A. G., Baloni, P., Price, N. D., Hood, L., & Hadlock, J. J. (2023). Timing of selective serotonin reuptake inhibitor use and risk for preterm birth and related adverse events. medRxiv. https://doi.org/10.1101/2023.03.03.23286717 Cite Download
Johnson, J. P., Diener, C., Levine, A. E., Wilmanski, T., Suskind, D. L., Ralevski, A., Hadlock, J., Magis, A. T., Hood, L., Rappaport, N., & Gibbons, S. M. (2023). Generally-healthy individuals with aberrant bowel movement frequencies show enrichment for microbially-derived blood metabolites associated with impaired kidney function. bioRxiv. https://doi.org/10.1101/2023.03.04.531100 Cite Download
Molani, S., Hernandez, P. V., Roper, R. T., Duvvuri, V. R., Baumgartner, A. M., Goldman, J. D., Ertekin-Taner, N., Funk, C. C., Price, N. D., Rappaport, N., & Hadlock, J. J. (2022). Risk factors for severe COVID-19 differ by age for hospitalized adults. Scientific Reports, 12(1), 6568. https://doi.org/10.1038/s41598-022-10344-3 Cite
Piekos, S. N., Price, N. D., Hood, L., & Hadlock, J. J. (2022). The impact of maternal SARS-CoV-2 infection and COVID-19 vaccination on maternal-fetal outcomes. Reproductive Toxicology (Elmsford, N.Y.), S0890-6238(22)00153-8. https://doi.org/10.1016/j.reprotox.2022.10.003 Cite
Kwasniewski, M., Korotko, U., Chwialkowska, K., Niemira, M., Jaroszewicz, J., Sobala-Szczygiel, B., Puzanowska, B., Moniuszko-Malinowska, A., Pancewicz, S., Parfieniuk-Kowerda, A., Martonik, D., Zarebska-Michaluk, D., Simon, K., Pazgan-Simon, M., Mozer-Lisewska, I., Bura, M., Adamek, A., Tomasiewicz, K., Pawłowska, M., … Moniuszko, M. (2022). Implementation of the web-based calculator estimating odds ratio of severe COVID-19 for unvaccinated individuals in a country with high coronavirus-related death toll. Allergy. https://doi.org/10.1111/all.15524 Cite
Molani, S., Hernandez, P. V., Roper, R. T., Duvvuri, V. R., Baumgartner, A. M., Goldman, J. D., Ertekin-Taner, N., Funk, C. C., Price, N. D., Rappaport, N., & Hadlock, J. J. (2022). Risk factors for severe COVID-19 differ by age: a retrospective study of hospitalized adults [Preprint]. Public and Global Health. https://doi.org/10.1101/2022.02.02.22270287 Cite Download
Mease, P. J., Wei, Q., Chiorean, M., Iles-Shih, L., & Hadlock, J. (2022). Op0247 Risk Factors for Severe Covid-19 Outcomes: A Study of Immune-Mediated Inflammatory Diseases, Therapies and Comorbidities in a Large Us Healthcare System. Annals of the Rheumatic Diseases, 81(Suppl 1), 161–162. https://doi.org/10.1136/annrheumdis-2022-eular.2163 Cite Download
Watanabe, K., Wilmanski, T., Diener, C., Zimmer, A., Lincoln, B., Hadlock, J. J., Lovejoy, J. C., Magis, A. T., Hood, L., Price, N. D., & Rappaport, N. (2022). Multiomic investigations of Body Mass Index reveal heterogeneous trajectories in response to a lifestyle intervention. medRxiv. https://doi.org/10.1101/2022.01.20.22269601 Cite Download
Goldman, J. D., Wang, K., Röltgen, K., Nielsen, S. C. A., Roach, J. C., Naccache, S. N., Yang, F., Wirz, O. F., Yost, K. E., Lee, J.-Y., Chun, K., Wrin, T., Petropoulos, C. J., Lee, I., Fallen, S., Manner, P. M., Wallick, J. A., Algren, H. A., Murray, K. M., … Heath, J. R. (2022). Reinfection with SARS-CoV-2 and Waning Humoral Immunity: A Case Report. Vaccines, 11(1), 5. https://doi.org/10.3390/vaccines11010005 Cite Download
Duvvuri, V. R., Baumgartner, A., Molani, S., Hernandez, P. V., Yuan, D., Roper, R. T., Matos, W. F., Robinson, M., Su, Y., Subramanian, N., Goldman, J. D., Heath, J. R., & Hadlock, J. J. (2022). Angiotensin-Converting Enzyme (ACE) Inhibitors May Moderate COVID-19 Hyperinflammatory Response: An Observational Study with Deep Immunophenotyping. Health Data Science, 2022, 0002. https://doi.org/10.34133/hds.0002 Cite Download
Unni, D. R., Moxon, S. A. T., Bada, M., Brush, M., Bruskiewich, R., Caufield, J. H., Clemons, P. A., Dancik, V., Dumontier, M., Fecho, K., Glusman, G., Hadlock, J. J., Harris, N. L., Joshi, A., Putman, T., Qin, G., Ramsey, S. A., Shefchek, K. A., Solbrig, H., … Biomedical Data Translator Consortium. (2022). Biolink Model: A universal schema for knowledge graphs in clinical, biomedical, and translational science. Clinical and Translational Science, 15(8), 1848–1855. https://doi.org/10.1111/cts.13302 Cite Download
Fecho, K., Thessen, A. E., Baranzini, S. E., Bizon, C., Hadlock, J. J., Huang, S., Roper, R. T., Southall, N., Ta, C., Watkins, P. B., Williams, M. D., Xu, H., Byrd, W., Dančík, V., Duby, M. P., Dumontier, M., Glusman, G., Harris, N. L., Hinderer, E. W., … Biomedical Data Translator Consortium. (2022). Progress toward a universal biomedical data translator. Clinical and Translational Science. https://doi.org/10.1111/cts.13301 Cite
Molani, S., Baumgartner, A. M., Hwang, Y. M., Duvvuri, V. R., Goldman, J. D., & Hadlock, J. J. (2022). Time to reinfection and vaccine breakthrough SARS-CoV-2 infections: a retrospective cohort study. 2022.02.07.22270613. https://www.medrxiv.org/content/10.1101/2022.02.07.22270613v1 Cite Download
Baumgartner, A., Molani, S., Wei, Q., & Hadlock, J. (2022). Imputing Missing Observations with Time Sliced Synthetic Minority Oversampling Technique. ArXiv:2201.05634 [Physics, q-Bio, Stat]. http://arxiv.org/abs/2201.05634 Cite Download
Piekos, S. N., Roper, R. T., Hwang, Y. M., Sorensen, T., Price, N. D., Hood, L., & Hadlock, J. J. (2022). The effect of maternal SARS-CoV-2 infection timing on birth outcomes: a retrospective multicentre cohort study. The Lancet. Digital Health, 4(2), e95–e104. https://doi.org/10.1016/S2589-7500(21)00250-8 Cite Download
Su, Y., Yuan, D., Chen, D. G., Ng, R. H., Wang, K., Choi, J., Li, S., Hong, S., Zhang, R., Xie, J., Kornilov, S. A., Scherler, K., Pavlovitch-Bedzyk, A. J., Dong, S., Lausted, C., Lee, I., Fallen, S., Dai, C. L., Baloni, P., … Heath, J. R. (2022). Multiple Early Factors Anticipate Post-Acute COVID-19 Sequelae. Cell, 0(0). https://doi.org/10.1016/j.cell.2022.01.014 Cite Download
Diaz, G. A., Christensen, A. B., Pusch, T., Goulet, D., Chang, S.-C., Grunkemeier, G. L., McKelvey, P. A., Robicsek, A., French, T., Parsons, G. T., Doherty, G., Laurenson, C., Roper, R., Hadlock, J., Cover, C. J., Footer, B., Robinson, P., Micikas, M., Marfori, J. E., … Goldman, J. D. (2021). Remdesivir and Mortality in Patients With Coronavirus Disease 2019. Clinical Infectious Diseases, ciab698. https://doi.org/10.1093/cid/ciab698 Cite Download
Jiang, Y., Duffy, F., Hadlock, J., Raappana, A., Styrchak, S., Beck, I., Mast, F. D., Miller, L. R., Chour, W., Houck, J., Armistead, B., Duvvuri, V. R., Yeung, W., Haglund, M., Wallner, J., Wallick, J. A., Hardy, S., Oldroyd, A., Ko, D., … Harrington, W. E. (2021). Angiotensin II receptor I auto-antibodies following SARS-CoV-2 infection. PloS One, 16(11), e0259902. https://doi.org/10.1371/journal.pone.0259902 Cite Download
Lee, J. W., Su, Y., Baloni, P., Chen, D., Pavlovitch-Bedzyk, A. J., Yuan, D., Duvvuri, V. R., Ng, R. H., Choi, J., Xie, J., Zhang, R., Murray, K., Kornilov, S., Smith, B., Magis, A. T., Hoon, D. S. B., Hadlock, J. J., Goldman, J. D., Price, N. D., … Heath, J. R. (2021). Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19. Nature Biotechnology. https://doi.org/10.1038/s41587-021-01020-4 Cite Download
Lee, J. Y., Molani, S., Fang, C., Jade, K., O’Mahony, D. S., Kornilov, S. A., Mico, L. T., & Hadlock, J. J. (2021). Ambulatory Risk Models for the Long-Term Prevention of Sepsis: Retrospective Study. JMIR Medical Informatics, 9(7), e29986. https://doi.org/10.2196/29986 Cite Download
Su, Y., Yuan, D., Chen, D. G., Wang, K., Choi, J., Dai, C. L., Hong, S., Zhang, R., Xie, J., Li, S., Scherler, K., Pavlovitch-Bedzyk, A. J., Dong, S., Lausted, C., Ng, R. H., Lee, I., Fallen, S., Kornilov, S. A., Baloni, P., … Heath, J. R. (2021). Heterogeneous immunological recovery trajectories revealed in post-acute COVID-19. MedRxiv, 2021.03.19.21254004. https://doi.org/10.1101/2021.03.19.21254004 Cite Download
Dai, C. L., Kornilov, S. A., Roper, R. T., Cohen-Cline, H., Jade, K., Smith, B., Heath, J. R., Diaz, G., Goldman, J. D., Magis, A. T., & Hadlock, J. J. (2021). Characteristics and Factors Associated with COVID-19 Infection, Hospitalization, and Mortality Across Race and Ethnicity. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America. https://doi.org/10.1093/cid/ciab154 Cite Download
Goldman, J. D., Wang, K., Röltgen, K., Nielsen, S. C. A., Roach, J. C., Naccache, S. N., Yang, F., Wirz, O. F., Yost, K. E., Lee, J.-Y., Chun, K., Wrin, T., Petropoulos, C. J., Lee, I., Fallen, S., Manner, P. M., Wallick, J. A., Algren, H. A., Murray, K. M., … Heath, J. R. (2020). Reinfection with SARS-CoV-2 and Failure of Humoral Immunity: a case report (p. 2020.09.22.20192443). https://www.medrxiv.org/content/10.1101/2020.09.22.20192443v1 Cite Download
Su, Y., Chen, D., Yuan, D., Lausted, C., Choi, J., Dai, C. L., Voillet, V., Duvvuri, V. R., Scherler, K., Troisch, P., Baloni, P., Qin, G., Smith, B., Kornilov, S. A., Rostomily, C., Xu, A., Li, J., Dong, S., Rothchild, A., … Heath, J. R. (2020). Multi-omics resolves a sharp disease-state shift between mild and moderate COVID-19. Cell, S0092867420314446. https://doi.org/10.1016/j.cell.2020.10.037 Cite Download
Fecho, K., Ahalt, S. C., Arunachalam, S., Champion, J., Chute, C. G., Davis, S., Gersing, K., Glusman, G., Hadlock, J., Lee, J., Pfaff, E., Robinson, M., Sid, E., Ta, C., Xu, H., Zhu, R., Zhu, Q., Peden, D. B., & Biomedical Data Translator Consortium. (2019). Sex, obesity, diabetes, and exposure to particulate matter among patients with severe asthma: Scientific insights from a comparative analysis of open clinical data sources during a five-day hackathon. Journal of Biomedical Informatics, 100, 103325. https://doi.org/10.1016/j.jbi.2019.103325 Cite
Ahalt, S. C., Chute, C. G., Fecho, K., Glusman, G., Hadlock, J., Taylor, C. O., Pfaff, E. R., Robinson, P. N., Solbrig, H., Ta, C., Tatonetti, N., Weng, C., & Biomedical Data Translator Consortium. (2019). Clinical Data: Sources and Types, Regulatory Constraints, Applications. Clinical and Translational Science. https://doi.org/10.1111/cts.12638 Cite Download
Robinson, M., Hadlock, J., Yu, J., Khatamian, A., Aravkin, A. Y., Deutsch, E. W., Price, N. D., Huang, S., & Glusman, G. (2018). Fast and simple comparison of semi-structured data, with emphasis on electronic health records. BioRxiv, 293183. https://doi.org/10.1101/293183 Cite Download